Yes, and it’s easier than you might think.
If you’re driving yourself it generally adds extra travel time, but the flexibility of your own vehicle is generally a bonus.
Weekend trips into Outback Queensland are easiest driving from Brisbane, Rockhampton or Townsville.
Flying and hiring a vehicle is popular for those who like the flexibility of a vehicle but want to cut out the extra travel time.
You can also see the region by tours to reduce the potential stress of driving. Tours are available from the coast or once you arrive in-region.